|Location:||Stanford, CA USA|
|Lab Name:||the Brunet lab|
Our laboratory studies the molecular mechanisms of aging and longevity. We are particularly interested in the aging of the nervous system. An emerging concept is that organismal aging, long thought to be a byproduct of wear and tear, is actually a highly controlled process, regulated by a combination of genetic and environmental factors. The search for genes that play a central role in controlling lifespan in several species has converged on components of the signaling pathway that connects insulin/insulin like growth factors to FOXO transcription factors and on the family of Sirtuin deacetylases.