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Potential of chromatin modifying compounds for the treatment of Alzheimer's disease

In this review we provide an overview of the histone deacetylase enzymes, with a focus on enzymes that have been identified to have an important role in the pathobiology of Alzheimer's disease. Further, we discuss the potential for pharmacological intervention with chromatin modifying compounds that modulate histone deacetylase enzymes. http://www.pathobiologyofaging.net/index.php/pba/article/view/14980/html

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